Senior Scientist Downstream Processing ()

Beschrijving:

Our client is a young private biotechnology company focused on creating technology to develop new healthcare products. They develop enzyme replacement therapies for lysosomal storage diseases  as well as improved antibodies, using a glyco-engineered yeast production host and proprietary, purpose-built development tools.

 

The research group in Ghent consists of +35 people working in the field of yeast protein expression systems. The downstream processing team  holds 4 team members.

This position is for a full-time Senior Scientist DSP, who is able to overlook protein purification manufacturing processes in a multiple product pilot facility.

We are looking for a highly motivated senior scientist, who is co-responsible for the purification protocols and can adequately report the results to the Head of CMC.

The following tasks are common in this line of work:

• Responsible for  technology transfer of downstream  processes to the CMO
• Responsible from Tox to clinical supply
• Review of production documentation in close collaboration with the CMO
• (Planning and performing small-scale lab trials to investigate novel purification routes)
• (Scaling-up of research protocols to be applicable in large scale GMP manufacturing)
• Experience with Large scale column chromatography, tangential flow filtration,  filtration
• Responsible for planning (personnel, raw materials,..) and execution of the Downstream process at the
• Key team member for process validation
• Work closely with Fermentation team and Quality team to ensure that the purification protocols and processes are compliant and ready for tech transfer to CMO
• Responsible for tech transfer and follow-up at CMO site where large scale production will be executed

 

•  
• Master or PhD in Life Sciences, Biochemical engineering or Biological sciences
• Min. 8 years of relevant large scale protein purification experience, in a GMP environment
• Good knowledge of GMP
• Good problem-solving skills. Team player, driven and creative
• Accurate , pro-active and Strong attention to detail
• result-oriented, able to work independently
• Developed communication skills
• Eligible to live and work in Belgium
• Willingness to travel in Europe (+30%)

   

• A competitive salary package and benefits
• A dynamic and enthusiastic work environment with project, process and people responsabilities in an innovative company

 

You can apply by sending your CV to

Mariette Teuwens 

HR/Recruitment Officer

+32 3 808 21 79

SENIOR SCIENTIST DOWNSTREAM PROCESSING

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