Senior Scientist Downstream Processing ()

Beschrijving:

Our client is a young private biotechnology company focused on creating technology to develop new healthcare products. They develop enzyme replacement therapies for lysosomal storage diseases  as well as improved antibodies, using a glyco-engineered yeast production host and proprietary, purpose-built development tools.

 

The research group in Ghent consists of +35 people working in the field of yeast protein expression systems. The downstream processing team  holds 4 team members.

This position is for a full-time Senior Scientist DSP, who is able to overlook protein purification manufacturing processes in a multiple product pilot facility.

We are looking for a highly motivated senior scientist, who is co-responsible for the purification protocols and can adequately report the results to the Head of CMC.

The following tasks are common in this line of work:

  • Responsible for  technology transfer of downstream  processes to the CMO
  • Responsible from Tox to clinical supply
  • Review of production documentation in close collaboration with the CMO
  • (Planning and performing small-scale lab trials to investigate novel purification routes)
  • (Scaling-up of research protocols to be applicable in large scale GMP manufacturing)
  • Experience with Large scale column chromatography, tangential flow filtration,  filtration
  • Responsible for planning (personnel, raw materials,..) and execution of the Downstream process at the
  • Key team member for process validation
  • Work closely with Fermentation team and Quality team to ensure that the purification protocols and processes are compliant and ready for tech transfer to CMO
  • Responsible for tech transfer and follow-up at CMO site where large scale production will be executed

 

  •  
  • Master or PhD in Life Sciences, Biochemical engineering or Biological sciences
  • Min. 8 years of relevant large scale protein purification experience, in a GMP environment
  • Good knowledge of GMP
  • Good problem-solving skills. Team player, driven and creative
  • Accurate , pro-active and Strong attention to detail
  • result-oriented, able to work independently
  • Developed communication skills
  • Eligible to live and work in Belgium
  • Willingness to travel in Europe (+30%)

     

  • A competitive salary package and benefits
  • A dynamic and enthusiastic work environment with project, process and people responsabilities in an innovative company

 

You can apply by sending your CV to

Mariette Teuwens 

HR/Recruitment Officer

+32 3 808 21 79

SENIOR SCIENTIST DOWNSTREAM PROCESSING

Categorie: 

 


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